Etymologia: Creutzfeldt-Jakob Disease
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43. Jayanthi P, Thomas P, Bindhu P, Krishnapillai R. Prion diseases in humans: oral and dental implications. N Am J Med Sci. 2013;5:399–403. http://dx.doi.org/10.4103/1947-2714.115766 44. Peden A, McCardle L, Head MW, Love S, Ward HJ, Cousens SN, et al. Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia. Haemophilia. 2010; 16:296–304. http://dx.doi.org/10.1111/j.1365-2516. 2009.02181.x 45. Llewelyn CA, Hewitt PE, Knight RS, Amar K, Cousens S, Mackenzie J, et al. Possible transmission of variant CreutzfeldtJakob disease by blood transfusion. Lancet. 2004;363:417–21. http://dx.doi.org/10.1016/S0140-6736(04)15486-X 46. Lefrère JJ, Hewitt P. From mad cows to sensible blood transfusion: the risk of prion transmission by labile blood components in the United Kingdom and in France. Transfusion. 2009;49:797–812. http://dx.doi.org/10.1111/j.1537-2995.2008.02044.x 47. Edgeworth JA, Farmer M, Sicilia A, Tavares P, Beck J, Campbell T, et al. Detection of prion infection in variant Creutzfeldt-Jakob disease: a blood-based assay. Lancet. 2011;377:487–93. http://dx.doi.org/10.1016/S0140-6736(10)62308-2 48. Jackson GS, Burk-Rafel J, Edgeworth JA, Sicilia A, Abdilahi S, Korteweg J, et al. A highly specific blood test for vCJD. Blood. 2014;123:452–3. http://dx.doi.org/10.1182/blood-2013-11-539239
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Creutzfeldt-Jakob disease: A case report
Background: Creutzfeldt-Jakob disease (CJD) as a life-threatening neurodegenerative disorder is not usually diagnosed in early stages of the disease because of a variety in its clinical manifestations. This study aimed to present a middle-aged woman with psychiatric symptoms who ultimately was diagnosed as a CJD case. Case presentation: This 48-year-old woman had progressive symptoms of depres...
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متن کاملFirst hundred cases of variant Creutzfeldt-Jakob disease: retrospective case note review of early psychiatric and neurological features.
OBJECTIVE To describe the early psychiatric and neurological features of variant Creutzfeldt-Jakob disease. DESIGN Cohort study. SETTING National surveillance system for Creutzfeldt-Jakob disease in the United Kingdom. PARTICIPANTS The first 100 cases of variant Creutzfeldt-Jakob disease identified in the United Kingdom. MAIN OUTCOME MEASURES The timing and nature of early psychiatric a...
متن کاملComputed tomography findings in 15 cases of Creutzfeldt-Jakob disease with histological verification.
Computed tomography (CT) was normal in twelve of fifteen patients with definite Creutzfeldt-Jakob disease. In two patients CT showed mild sulcal widening, while marked ventricular enlargement and moderate cortical atrophy were seen in a patient who had both Creutzfeldt-Jakob disease and normal pressure hydrocephalus. No correspondence was observed between CT findings, severity of the clinical p...
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Introduction Although Creutzfeldt-Jakob disease (CJD) is rare, its rapid course, its infection control implications and the link between bovine spongiform encephalopathy and variant Creutzfeldt-Jakob disease (vCJD) make this disease relevant to all clinicians. The emergence of vCJD has prompted an explosion in the amount of research into the disorder, leading to new developments in both diagnos...
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